Description

Methyl 4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is a high-purity organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing thiophene or heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its boronate ester functionality for structural diversification.
• Material Science: Employed in the creation of organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl systems.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry and process chemistry research in both university and corporate laboratory settings.

Basic Information

Product Name	Methyl 4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate
CAS No.	1040281-86-4
Molecular Formula	C12H19BO4S
Molecular Weight	270.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylic acid methyl ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 4-(pinacolatoboron)thiophene-2-carboxylate; 4-(Pinacolatoboran-2-yl)thiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.