Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbaldehyde is a high-value, multifunctional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex heterocyclic architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiophene or biaryl motifs for therapeutic agents.
• Agrochemical Synthesis: Used to construct novel herbicide and pesticide molecules by introducing the functionalized thiophene aldehyde moiety into complex structures.
• Organic Electronic Materials: Serves as a fundamental building block for creating conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its aldehyde and boronate ester functionalities.
• Chemical Research & Development: A versatile reagent for constructing complex molecular libraries via parallel synthesis and combinatorial chemistry in drug discovery programs.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of dyes, pigments, and other specialty chemicals requiring precise molecular assembly.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbaldehyde
CAS No.	1040281-83-1
Molecular Formula	C11H15BO3S
Molecular Weight	238.11 g/mol
Synonyms	2-Formylthiophene-5-boronic acid pinacol ester; Thiophene-2-carboxaldehyde, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Pinacolatoboryl)thiophene-2-carbaldehyde; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiophenecarboxaldehyde; 5-Borono-2-thiophenecarboxaldehyde pinacol ester; 2-Thiophenecarboxaldehyde, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Pinacolboron)thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with full analytical data are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and supply reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to maximize shelf-life stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.