Description

3'-Bromo-[1,1'-Biphenyl]-3-Carbonitrile is a high-purity biphenyl derivative featuring both bromo and cyano functional groups, making it a versatile and valuable synthetic intermediate. This compound is critical for facilitating complex coupling reactions and constructing advanced molecular architectures in pharmaceutical and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in creating complex biaryl structures common in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and nitrile groups for further functionalization.
• Material Science Precursor: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and advanced polymers for electronic applications.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine substituent.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel phosphine or nitrogen-based ligands for catalytic systems.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Item	Details
Product Name	3'-Bromo-[1,1'-Biphenyl]-3-Carbonitrile
CAS No.	1040141-34-1
Molecular Formula	C13H8BrN
Molecular Weight	258.12 g/mol
Synonyms	3'-Bromobiphenyl-3-carbonitrile; 3-Bromo-3'-cyanobiphenyl; [1,1'-Biphenyl]-3-carbonitrile, 3'-bromo-; 3-Cyano-3'-bromobiphenyl; 3-(3-Bromophenyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3'-Bromo-[1,1'-Biphenyl]-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal standards. Our quality commitment ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.