Description

5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a high-value boronic ester derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the stability and reactivity of the boronate group.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and OFETs, where fluorinated aromatic units are critical for tuning electronic properties.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming reactions and synthesizing complex molecular libraries.

Basic Information

Product Name	5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
CAS No.	1038828-32-8
Molecular Formula	C12H16BFO3
Molecular Weight	238.07 g/mol
Synonyms	2-(5-Fluoro-2-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 5-Fluoro-2-hydroxybenzeneboronic acid pinacol ester; (5-Fluoro-2-hydroxyphenyl)boronic acid pinacol ester; 5-Fluoro-2-(pinacolatoboryl)phenol; 1038828-32-8; 5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (PIN).
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.