Description

4-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is a specialized boronic acid derivative featuring a pyrrolidine-substituted benzyl group. This structural motif makes it a valuable advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical R&D departments for the development of novel active compounds, particularly in medicinal chemistry applications.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures for drug discovery.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and material science applications.
• Chemical Biology Probes: Facilitates the creation of molecular probes for studying biological processes and protein interactions.
• Advanced Material Precursor: Acts as a monomer or functionalizing agent in the development of organic electronic materials and polymers.

Basic Information

Product Name	4-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid
CAS No.	1036991-20-4
Molecular Formula	C12H18BNO2
Molecular Weight	219.09 g/mol
Synonyms	[4-(1-Pyrrolidinylmethyl)phenyl]boronic Acid; 4-(Pyrrolidin-1-ylmethyl)benzeneboronic Acid; 4-(1-Pyrrolidinylmethyl)benzeneboronic Acid; 4-(Pyrrolidinomethyl)phenylboronic Acid; B-[4-(1-Pyrrolidinylmethyl)phenyl]boronic Acid; 4-(N-Pyrrolidinylmethyl)phenylboronic Acid; 1036991-20-4
EINECS	Contact for details

Quality Control

Our 4-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.