Description

1-Ethyl-4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoyl]Piperazine is a sophisticated boronic ester derivative, a key intermediate in modern pharmaceutical and agrochemical synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex carbon-carbon bonds. This high-purity building block is essential for research chemists and process development teams in pharmaceutical R&D, agrochemical discovery, and advanced material science.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity ligands for target identification and protein profiling studies.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to introduce functionalized aryl groups into molecular scaffolds.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	1-Ethyl-4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoyl]Piperazine
CAS No.	1036990-36-9
Molecular Formula	C19H29BN2O3
Molecular Weight	344.26 g/mol
Synonyms	1-Ethyl-4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine; 3-(1-Ethylpiperazine-4-carbonyl)phenylboronic acid pinacol ester; 1-Ethyl-4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]piperazine; (3-(4-Ethylpiperazine-1-carbonyl)phenyl)boronic acid pinacol ester; 1036990-36-9; AKOS025310693; A1-03427
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.