Description

4-[(1-Azetidinyl)Methyl]Phenylboronic Acid Pinacol Ester is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound is crucial for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those containing azetidine and biaryl motifs for targeted therapies.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products through efficient cross-coupling strategies.
• Material Science: Serves as a precursor for synthesizing organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents for studying biological systems.
• Academic & R&D Laboratories: Essential for methodological development and exploratory synthesis in organic and medicinal chemistry.
• Scale-up Process Chemistry: Used in pilot plants and manufacturing for the efficient, large-scale production of complex target molecules.

Basic Information

Product Name	4-[(1-Azetidinyl)Methyl]Phenylboronic Acid Pinacol Ester
CAS No.	1036990-23-4
Molecular Formula	C16H24BNO2
Molecular Weight	273.18 g/mol
Synonyms	4-(Azetidin-1-ylmethyl)phenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]azetidine; 4-(Azetidin-1-ylmethyl)benzeneboronic acid pinacol ester; Azetidine-1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]; (4-(Azetidin-1-ylmethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-[(1-Azetidinyl)Methyl]Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.