Description

1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile reagent for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry for creating heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and molecular probes for studying biological systems.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis in fine chemical manufacturing.

Basic Information

Product Name	1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1036714-06-3
Molecular Formula	C10H17BN2O2
Molecular Weight	208.07 g/mol
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrazole; 1-Methyl-4-(pinacolboranyl)-1H-pyrazole; 1-Methylpyrazole-4-boronic acid pinacol ester; 1-Methyl-1H-4-pyrazoleboronic acid pinacol ester; 1-Methyl-4-pyrazoleboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.