Description

Methyl 4-(2-Bromophenyl)-2,4-Dioxobutanoate is a high-purity, specialized organic building block crucial for advanced synthetic chemistry. This compound serves as a key intermediate in the development of complex molecules, offering a reactive β-ketoester moiety adjacent to a brominated aromatic ring. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and materials science for constructing novel heterocyclic frameworks and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for constructing fused heterocycles and complex molecular architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and cyclization processes.
• Chemical Synthesis: Employed as a versatile building block for the preparation of more complex β-keto esters, diketones, and functionalized aromatics.

Basic Information

Product Name	Methyl 4-(2-Bromophenyl)-2,4-Dioxobutanoate
CAS No.	1035235-10-9
Molecular Formula	C11H9BrO4
Molecular Weight	285.09 g/mol
Synonyms	Methyl 2-bromobenzoylacetate; 4-(2-Bromophenyl)-2,4-dioxobutanoic acid methyl ester; 2-Bromophenyl 2,4-dioxobutanoate methyl ester; Methyl (2-bromobenzoyl)acetate; 2-Bromobenzoylacetic acid methyl ester; Butanoic acid, 4-(2-bromophenyl)-2,4-dioxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(2-Bromophenyl)-2,4-Dioxobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.