Description

4-Ethynylbenzeneboronic Acid Pinacol Ester, 95% is a high-purity, protected boronic acid derivative essential for advanced organic synthesis and materials science. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in pharmaceutical development, agrochemical research, and the creation of novel organic electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and boronic acids, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile synthon for constructing active pharmaceutical ingredients (APIs) and complex bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-alkyne motifs.
• Materials Science & Organic Electronics: A precursor for conjugated polymers, molecular wires, and organic light-emitting diodes (OLEDs) due to its ethynyl functional group.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology & Bioconjugation: Useful for tagging biomolecules via click chemistry reactions involving the terminal alkyne.

Basic Information

Product Name	4-Ethynylbenzeneboronic Acid Pinacol Ester, 95%
CAS No.	1034287-04-1
Molecular Formula	C₁₄H₁₇BO₂
Molecular Weight	228.10 g/mol
Synonyms	4-Ethynylphenylboronic Acid Pinacol Ester; 1-Ethynyl-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; p-Ethynylbenzeneboronic Acid Pinacol Ester; 2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Ethynylbenzeneboronic Acid, Pinacol Ester; Boronic acid, B-(4-ethynylphenyl)-, 1,1-dimethylethyl ester (9CI); (4-Ethynylphenyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 4-Ethynylbenzeneboronic Acid Pinacol Ester, 95% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.