Description

(S)-3-(2-Amino-3-Methylbutanamido)Propane-1-Sulfonic Acid is a high-purity, non-natural amino acid derivative featuring a sulfonic acid group, offering unique chemical functionality and stereochemical specificity. This compound is a critical chiral building block and intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly protease inhibitors and other targeted therapies.
• Peptide Modification: Used to introduce a sulfonic acid moiety into peptide sequences, altering solubility, stability, and biological activity for research and therapeutic peptides.
• Bioconjugation & Linker Chemistry: Serves as a functional handle for bioconjugation strategies, enabling the attachment of drugs, labels, or other molecules to proteins or solid supports.
• Chemical Biology Research: Employed as a tool compound or building block in studying enzyme-substrate interactions, signal transduction pathways, and protein function.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-3-(2-Amino-3-Methylbutanamido)Propane-1-Sulfonic Acid
CAS No.	1034190-08-3
Molecular Formula	C9H20N2O4S
Molecular Weight	252.33 g/mol
Synonyms	L-Valine, N-[3-(sulfooxy)propyl]-; 3-[(2S)-2-Amino-3-methylbutanamido]propane-1-sulfonic Acid; (S)-3-(2-Amino-3-methylbutyramido)propane-1-sulfonic Acid; H-Val-NH-(CH2)3-SO3H; N-(3-Sulfopropyl)-L-valinamide; Valine sulfopropyl amide; L-Valine amide of 3-aminopropanesulfonic acid
EINECS	Contact for details

Quality Control

Our (S)-3-(2-Amino-3-Methylbutanamido)Propane-1-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.