Description

3,3,3-Trifluoropropane-1-Sulphonamide is a high-value organofluorine building block featuring a reactive sulphonamide group. This compound is essential for medicinal chemistry and advanced material science, enabling the precise introduction of trifluoromethyl and sulphonamide functionalities into target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of bioactive molecules, particularly sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or modifier in the production of fluorinated polymers and specialty coatings with unique surface properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and molecular recognition.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological processes.
• Fluorine Chemistry Research: A valuable reagent for exploring new fluorination methodologies and reaction pathways.

Basic Information

Item	Detail
Product Name	3,3,3-Trifluoropropane-1-Sulphonamide
CAS No.	1033906-44-3
Molecular Formula	C₃H₆F₃NO₂S
Molecular Weight	177.15 g/mol
Synonyms	3,3,3-Trifluoropropanesulfonamide; 3,3,3-Trifluoro-1-propanesulfonamide; 1-Propanesulfonamide, 3,3,3-trifluoro-; Trifluoropropylsulfonamide; TFPSA; 3,3,3-Trifluoropropane-1-sulfonamide; 3,3,3-Trifluoropropanesulphonamide
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropane-1-Sulphonamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.