Description

1-(2-Bromo-4-Chlorophenyl)-2,2,2-Trifluoroethanone is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. Its unique halogenated aromatic structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a key precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create specialized ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	1-(2-Bromo-4-Chlorophenyl)-2,2,2-Trifluoroethanone
CAS No.	1033805-23-0
Molecular Formula	C8H3BrClF3O
Molecular Weight	287.46 g/mol
Synonyms	2-Bromo-4-chloro-α,α,α-trifluoroacetophenone; 2'-Bromo-4'-chloro-2,2,2-trifluoroacetophenone; 1-(2-Bromo-4-chlorophenyl)-2,2,2-trifluoroethan-1-one; α,α,α-Trifluoro-2-bromo-4-chloroacetophenone; 2-Bromo-4-chlorophenyl trifluoromethyl ketone; (2-Bromo-4-chlorophenyl)(trifluoromethyl)methanone; TFAP-BrCl derivative
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Chlorophenyl)-2,2,2-Trifluoroethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.