Description

1,1'-Biphenyl, 2-Bromo-4'-(1,1-Dimethylethyl)- is a high-purity, synthetically valuable biphenyl derivative, distinguished by its bromine and tert-butyl substituents. This compound serves as a crucial advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in constructing complex biaryl and heterocyclic scaffolds common in modern therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the biphenyl core provides structural stability and bioactivity.
• Ligand & Catalyst Development: Serves as a foundational structure for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for conjugated polymers.
• Chemical Research & Development: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex, functionalized biphenyl systems.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for high-value industrial and research applications.

Basic Information

Product Name	1,1'-Biphenyl, 2-Bromo-4'-(1,1-Dimethylethyl)-
CAS No.	1033692-34-0
Molecular Formula	C16H17Br
Molecular Weight	289.21 g/mol
Synonyms	2-Bromo-4'-tert-butylbiphenyl; 4'-tert-Butyl-2-bromobiphenyl; 2-Bromo-4'-(1,1-dimethylethyl)-1,1'-biphenyl; 2-Bromo-4'-tert-butyl-1,1'-biphenyl; 2-Bromo-4'-(tert-butyl)biphenyl; 1,1'-Biphenyl, 2-bromo-4'-(1,1-dimethylethyl)-; 2-Bromo-4'-tert-butylbiphenyl
EINECS	Contact for details

Quality Control

Our 1,1'-Biphenyl, 2-Bromo-4'-(1,1-Dimethylethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.