Description

[1-(4-Fluorobenzyl)-3-Oxo-2-Piperazinyl]Acetic Acid is a high-purity pharmaceutical intermediate and building block of significant importance in modern synthetic chemistry. This compound is valued for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic structures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Used as a key precursor in the research and development of new Active Pharmaceutical Ingredients (APIs) with piperazine-based pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP conditions for clinical trial material production.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	[1-(4-Fluorobenzyl)-3-Oxo-2-Piperazinyl]Acetic Acid
CAS No.	1033600-10-0
Molecular Formula	C13H15FN2O3
Molecular Weight	266.27 g/mol
Synonyms	2-[[1-[(4-Fluorophenyl)methyl]-3-oxo-2-piperazinyl]acetic acid; 2-(1-(4-Fluorobenzyl)-3-oxopiperazin-2-yl)acetic acid; 1-(4-Fluorobenzyl)-3-oxo-2-piperazineacetic acid; (1-(4-Fluorobenzyl)-3-oxo-2-piperazinyl)acetic acid; 1033600-10-0; 2-(1-(4-Fluorobenzyl)-3-oxopiperazin-2-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our [1-(4-Fluorobenzyl)-3-Oxo-2-Piperazinyl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.