Description

2-[4-(Hydroxymethyl)Piperidino]-5-Nitrobenzenecarbaldehyde is a specialized nitrobenzaldehyde derivative featuring a hydroxymethyl-substituted piperidine moiety, making it a valuable multifunctional synthetic intermediate. This compound is particularly significant for its role in constructing complex molecular architectures, especially in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro and aldehyde functional groups for further derivatization.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional monomers where the aldehyde group enables further polymerization or cross-linking.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Dye and Pigment Intermediate: Acts as an intermediate in the production of advanced nitroaromatic dyes and organic pigments.

Basic Information

Product Name	2-[4-(Hydroxymethyl)Piperidino]-5-Nitrobenzenecarbaldehyde
CAS No.	1033463-38-5
Molecular Formula	C14H18N2O4
Molecular Weight	278.31 g/mol
Synonyms	5-Nitro-2-[4-(hydroxymethyl)piperidin-1-yl]benzaldehyde; 2-(4-(Hydroxymethyl)piperidin-1-yl)-5-nitrobenzaldehyde; 1-[2-Formyl-4-nitrophenyl]-4-piperidinemethanol; 4-(Hydroxymethyl)-1-(2-formyl-4-nitrophenyl)piperidine; 5-Nitro-2-(4-hydroxymethyl-1-piperidyl)benzaldehyde; Benzaldehyde, 2-[4-(hydroxymethyl)-1-piperidinyl]-5-nitro-; 1033463-38-5
EINECS	Contact for details

Quality Control

Our 2-[4-(Hydroxymethyl)Piperidino]-5-Nitrobenzenecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.