Description

2-Dimethylamino-Pyrimidine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic laboratories and CROs (Contract Research Organizations).
• Scale-up & Process Chemistry: Suitable for use in process optimization and pilot-scale synthesis under GMP-like conditions for critical pharmaceutical intermediates.

Basic Information

Item	Details
Product Name	2-Dimethylamino-Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	1032759-30-0
Molecular Formula	C13H22BN3O2
Molecular Weight	263.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylpyrimidin-2-amine; 2-(Dimethylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Dimethylaminopyrimidine-5-boronic acid pinacol ester; (2-(Dimethylamino)pyrimidin-5-yl)boronic acid pinacol ester; 2-DMAP-5-BPin
EINECS	Contact for details

Quality Control

Every batch of 2-Dimethylamino-Pyrimidine-5-Boronic Acid Pinacol Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other analytical techniques is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.