Description

2-(tert-Butoxycarbonylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester is a high-value, protected boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient, high-yielding cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of new active ingredients, functional molecules, and electronic materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in oncology, antiviral, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyrimidine-based structures.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in university and CRO (Contract Research Organization) laboratories worldwide.
• Scale-up & Process Chemistry: Suitable for use in route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	2-(tert-Butoxycarbonylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester
CAS No.	1032758-88-5
Molecular Formula	C15H24BN3O4
Molecular Weight	321.18 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)pyrimidine-5-boronic acid pinacol ester; 2-(Boc-amino)pyrimidine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine, N-Boc protected; 2-[(tert-Butoxycarbonyl)amino]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; Boc-protected 2-aminopyrimidine-5-boronic acid pinacol ester; 2-(N-Boc-amino)-5-(pinacolboronato)pyrimidine; 1032758-88-5; tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.