Description

6-(tert-Butyloxycarbonylamino) Pyridine-3-Boronic Acid Pinacol Ester is a high-value, protected boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions while protecting the sensitive amine functionality, enabling the precise construction of complex heterocyclic scaffolds. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of active ingredients, intermediates, and novel chemical entities.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Research: Used in constructing novel pyridine-based herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science: Serves as a building block for creating functionalized organic ligands, polymers, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, bioconjugation reagents, and tagged compounds for studying biological systems.
• Academic & Contract Research: A vital reagent for methodology development and the synthesis of complex, bespoke molecules in research laboratories.

Basic Information

Product Name	6-(tert-Butyloxycarbonylamino) Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1032758-86-3
Molecular Formula	C₁₆H₂₅BN₂O₄
Molecular Weight	320.19 g/mol
Synonyms	6-((tert-Butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; 6-(Boc-amino)pyridin-3-ylboronic acid pinacol ester; 3-Pyridineboronic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester; Boc-protected 3-pyridylboronic acid pinacol ester; 6-(N-Boc-amino)-3-pyridylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-((tert-butoxycarbonyl)amino)pyridine; 2-((tert-Butoxycarbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 6-(tert-Butyloxycarbonylamino) Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.