Description

(3-Bromo-2-Cyanophenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both bromo and cyano substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for applications in Suzuki-Miyaura cross-coupling reactions and the synthesis of novel heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through cross-coupling chemistry.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and organic semiconductors, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs serving the global life sciences industry.

Basic Information

Product Name	(3-Bromo-2-Cyanophenyl)Boronic Acid
CAS No.	1032231-32-5
Molecular Formula	C7H5BBrNO2
Molecular Weight	225.84 g/mol
Synonyms	2-Cyano-3-bromophenylboronic acid; (3-Bromo-2-cyanophenyl)boronic acid; B-(3-Bromo-2-cyanophenyl)boronic acid; 3-Bromo-2-cyanobenzeneboronic acid; Boronic acid, B-(3-bromo-2-cyanophenyl)-; 1032231-32-5; AKOS025310999; FT-0697675
EINECS	Contact for details

Quality Control

Every batch of (3-Bromo-2-Cyanophenyl)Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.