Description

Cyclohexaneacetic Acid, 4-Phenyl-, Ethyl Ester, trans- CAS NO 1031336-66-9 is a high-purity, trans-configured ester derivative of phenyl-substituted cyclohexaneacetic acid, valued for its defined stereochemistry and functional group versatility. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, offering precise structural control. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry, process development, and the creation of novel materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex molecules in agrochemical, fragrance, and specialty polymer research.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in studies exploring new catalytic systems due to its defined stereogenic centers.
• Material Science: Intermediate for developing novel liquid crystals or specialty monomers with specific steric and electronic properties.
• Academic & Industrial R&D: Essential reference standard and starting material in synthetic organic chemistry laboratories for method development and scale-up studies.

Basic Information

Product Name	Cyclohexaneacetic Acid, 4-Phenyl-, Ethyl Ester, trans-
CAS No.	1031336-66-9
Molecular Formula	C16H22O2
Molecular Weight	246.34 g/mol
Synonyms	trans-4-Phenylcyclohexaneacetic Acid Ethyl Ester; Ethyl trans-4-Phenylcyclohexylacetate; trans-Ethyl 4-Phenylcyclohexylacetate; (trans-4-Phenylcyclohexyl)acetic Acid Ethyl Ester; Ethyl (trans-4-Phenylcyclohexyl)acetate; 4-Phenylcyclohexaneacetic acid, ethyl ester, trans-; (1r,4r)-Ethyl 4-phenylcyclohexylacetate
EINECS	Contact for details

Quality Control

Our Cyclohexaneacetic Acid, 4-Phenyl-, Ethyl Ester, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and GC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.