Description

2-(Bromomethyl)-3,4-Dichlorophenylboronic Acid, Pinacol Ester is a high-value, multi-functional organoboron building block, specifically engineered for advanced cross-coupling reactions. Its unique structure, featuring both a reactive bromomethyl handle and a protected boronic acid moiety, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific halogenated and boronate-functionalized scaffolds.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes due to its dual functionality.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Bromomethyl)-3,4-Dichlorophenylboronic Acid, Pinacol Ester
CAS No.	1030832-48-4
Molecular Formula	C13H16BBrCl2O2
Molecular Weight	366.89 g/mol
Synonyms	2-(Bromomethyl)-3,4-dichlorobenzeneboronic acid pinacol ester; 3,4-Dichloro-2-(bromomethyl)phenylboronic acid pinacol ester; (2-(Bromomethyl)-3,4-dichlorophenyl)boronic acid pinacol ester; B-[2-(Bromomethyl)-3,4-dichlorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[2-(bromomethyl)-3,4-dichlorophenyl]-1,3,2-dioxaborolane; 2-(Bromomethyl)-3,4-DCPB pinacol ester; Boronic acid, B-[2-(bromomethyl)-3,4-dichlorophenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3,4-Dichlorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard specification is designed to meet the exacting requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.