Description

2-Bromomethyl-4-Trifluoromethylbenzene Boronic Ester is a high-value, multi-functional organoboron intermediate critical for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced material development. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures with high efficiency and selectivity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and aryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the synthesis of functional polymers and dendrimers.

Basic Information

Product Name	2-Bromomethyl-4-Trifluoromethylbenzene Boronic Ester
CAS No.	1030832-46-2
Molecular Formula	C10H9BBrF3O2 (Typical for pinacol ester)
Molecular Weight	Contact for details
Synonyms	[4-(Bromomethyl)-3-(trifluoromethyl)phenyl]boronic acid pinacol ester; 2-Bromomethyl-α,α,α-trifluoro-p-tolylboronic acid pinacol ester; (4-(Bromomethyl)-3-(trifluoromethyl)phenyl)boronic acid pinacol ester; Boronic acid, B-[4-(bromomethyl)-3-(trifluoromethyl)phenyl]-, 1,1-dimethylethyl ester; 2-(Bromomethyl)-4-(trifluoromethyl)benzeneboronic acid pinacol ester; CAS 1030832-46-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethyl-4-Trifluoromethylbenzene Boronic Ester is manufactured and tested under strict quality management systems. We ensure compliance with rigorous internal specifications, which typically include identity confirmation by NMR and HPLC purity analysis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during aliquoting to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.