Description

(S)-(7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Yl)Carbamic Acid Isopropyl Ester is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it provides a critical, structurally defined building block for the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its role in constructing complex molecular architectures with high stereochemical fidelity, enabling the production of targeted, potent drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel, biologically active compounds, particularly for targeted cancer therapies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial precursor in the research and process development of new chemical entities (NCEs).
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex indole-based frameworks found in many modern pharmaceuticals.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs within drug discovery.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials and commercial APIs.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(S)-(7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Yl)Carbamic Acid Isopropyl Ester
CAS No.	1029691-23-3
Molecular Formula	C16H17N3O2
Molecular Weight	283.33 g/mol
Synonyms	(2S)-2-[(Isopropoxycarbonyl)amino]-1,2,3,4-tetrahydro-7-cyclopenta[b]indolecarbonitrile; (S)-2-((Isopropoxycarbonyl)amino)-1,2,3,4-tetrahydrocyclopenta[b]indole-7-carbonitrile; Isopropyl (2S)-2-amino-1,2,3,4-tetrahydrocyclopenta[b]indole-7-carboxylate derivative; (S)-Isopropyl (7-cyano-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl)carbamate; Chiral Tetrahydrocyclopentaindole Carbamate; (S)-Enantiomer of CN-THCPI-Carbamate
EINECS	Contact for details

Quality Control

Our (S)-(7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Yl)Carbamic Acid Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial methods for identity and impurity profiling, to ensure compliance with stringent industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.