Description

1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Imidazole-5-Boroni is a specialized organoboron reagent, a key building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acid derivatives.
• Pharmaceutical Intermediate Synthesis: Used in the construction of active pharmaceutical ingredients (APIs) and complex heterocyclic scaffolds.
• Agrochemical Development: Serves as a key intermediate in the synthesis of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Facilitates the labeling and modification of biomolecules for research and diagnostic applications.

Basic Information

Product Name	1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Imidazole-5-Boroni
CAS No.	1029684-37-4
Molecular Formula	C8H13BN2O
Molecular Weight	164.01 g/mol
Synonyms	1-(Tetrahydro-2H-pyran-2-yl)-1H-imidazole-5-boronic acid pinacol ester; 1-(THP)-1H-imidazole-5-boronic acid pinacol ester; 1-(Tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole; 1-(THP)-Imidazole-5-BPin; 1-(Tetrahydro-2H-pyran-2-yl)-1H-imidazol-5-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Imidazole-5-Boroni is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure high purity and consistent performance in sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive nature. Allow the sealed container to reach ambient temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.