Description

2-Phenylpyridine-3-Boronic Acid is a versatile boronic acid derivative and a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), advanced materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those containing biphenyl or heteroaryl motifs for oncology, CNS, and antiviral applications.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides by constructing specific aromatic frameworks essential for biological activity.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a reliable boronic acid partner for palladium-catalyzed carbon-carbon bond formation with aryl halides or triflates.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and inhibitors that target specific proteins or enzymes.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Phenylpyridine-3-Boronic Acid
CAS No.	1029654-14-5
Molecular Formula	C11H10BNO2
Molecular Weight	199.02 g/mol
Synonyms	(2-Phenylpyridin-3-yl)boronic Acid; 3-Borono-2-phenylpyridine; 2-Phenyl-3-pyridineboronic Acid; 2-Phenyl-3-pyridinylboronic Acid; 2-Phenyl-3-boronopyridine; 2-Phenylpyridine-3-boronic Acid Pinacol Ester (common derivative); B-(2-Phenyl-3-pyridinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Phenylpyridine-3-Boronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: ≥98.5%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.