Description

3,5-Difluoro-4-Hydroxybenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a key building block in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing difluorophenol or biphenyl motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Acts as a precursor for synthesizing molecular probes used in biochemical assays and diagnostic tools.

Basic Information

Product Name	3,5-Difluoro-4-Hydroxybenzeneboronic Acid Pinacol Ester, 96%
CAS No.	1029439-83-5
Molecular Formula	C₁₂H₁₅BF₂O₃
Molecular Weight	256.06 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(3,5-difluoro-4-hydroxyphenyl)-1,3,2-dioxaborolane; (3,5-Difluoro-4-hydroxyphenyl)boronic acid pinacol ester; 2-(3,5-Difluoro-4-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Difluoro-4-hydroxybenzeneboronic acid, pinacol ester; Pinacol (3,5-difluoro-4-hydroxyphenyl)boronate; Boronic acid, B-(3,5-difluoro-4-hydroxyphenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Hydroxybenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the specified 96% minimum assay. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.