Description

4,4,5,5-Tetramethyl-2-(4-((3-Methylbenzyl)Oxy)Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. Its value lies in its role as a versatile boronic ester, enabling critical carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality precursors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for forming biaryl and other carbon-carbon bonds in medicinal chemistry and material synthesis.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate structures.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor in the synthesis of advanced organic electronic materials and emissive layers.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and metal-organic frameworks (MOFs) for catalytic applications.
• Polymer Chemistry: Utilized to introduce boronate functional groups into polymer backbones for specialty materials.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): A valuable linker or component in the design of bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-((3-Methylbenzyl)Oxy)Phenyl)-1,3,2-Dioxaborolane
CAS No.	1029439-14-2
Molecular Formula	C20H25BO3
Molecular Weight	324.22 g/mol
Synonyms	[4-[(3-Methylphenyl)methoxy]phenyl]boronic acid pinacol ester; 2-[4-[(3-Methylbenzyl)oxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-((3-Methylbenzyl)oxy)phenylboronic acid pinacol ester; (4-((3-Methylbenzyl)oxy)phenyl)boronic acid pinacol ester; PINACOL [4-[(3-METHYLBENZYL)OXY]PHENYL]BORONATE; 4,4,5,5-Tetramethyl-2-[4-[(3-methylphenyl)methoxy]phenyl]-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(4-((3-Methylbenzyl)Oxy)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.