Description

2-Benzyloxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for demanding synthetic protocols, particularly Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Employed as a precursor for creating specialized ligands or functionalized materials for catalysis and material science applications.
• Organic Electronic Materials: A potential monomer or intermediate in the synthesis of conjugated polymers and small molecules for OLEDs, OFETs, and other optoelectronic devices.
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and bioconjugation tools due to its reactive boronate functionality after deprotection.

Basic Information

Product Name	2-Benzyloxyphenylboronic Acid, Pinacol Ester
CAS No.	1027757-13-6
Molecular Formula	C19H23BO3
Molecular Weight	310.20 g/mol
Synonyms	2-(Benzyloxy)phenylboronic acid pinacol ester; [2-(Phenylmethoxy)phenyl]boronic acid pinacol ester; 2-Benzyloxybenzeneboronic acid pinacol ester; 2-(Benzyloxy)phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Benzyloxy)phenylboronic acid neopentyl glycol ester (common alternative); B-[2-(Benzyloxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Each batch is characterized by NMR (1H, 13C, 11B), HPLC, and GC analysis to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all analytical results are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and supply reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Purity (GC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.