Description

3-Chloro-2,5-Dibromobenzotrifluoride is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring chlorine, bromine, and trifluoromethyl substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and halogen groups enhance lipophilicity and biological activity.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and intermolecular interactions.
• Cross-Coupling Reactions: An excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to create complex biaryl and heteroaryl structures.
• Functional Group Transformation: The bromine atoms provide handles for further functionalization via nucleophilic substitution or metal-halogen exchange, enabling diverse chemical libraries.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	3-Chloro-2,5-Dibromobenzotrifluoride
CAS No.	1027512-72-6
Molecular Formula	C7H2Br2ClF3
Molecular Weight	338.35 g/mol
Synonyms	1-Chloro-2,5-dibromo-3-(trifluoromethyl)benzene; 2,5-Dibromo-3-chlorobenzotrifluoride; 3-Chloro-2,5-dibromo-α,α,α-trifluorotoluene; Benzene, 1-chloro-2,5-dibromo-3-(trifluoromethyl)-; 2,5-Dibromo-3-chloro-α,α,α-trifluorotoluene; 3-Chloro-2,5-dibromo-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,5-Dibromobenzotrifluoride is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from techniques such as HPLC, GC, NMR, and IR spectroscopy are provided and available upon request. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.