Description

Potassium (E)-3-Methoxyprop-1-Enyltrifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, particularly Suzuki-Miyaura cross-couplings, with enhanced stability and handling compared to traditional boronic acids. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex bioactive molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by enabling the introduction of specific methoxy-substituted alkene motifs.
• Material Science & OLED Development: Serves as a building block for creating conjugated organic molecules used in organic light-emitting diodes (OLEDs) and electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: A fundamental tool in methodological organic chemistry research and process chemistry optimization for scale-up.

Basic Information

Product Name	Potassium (E)-3-Methoxyprop-1-Enyltrifluoroborate
CAS No.	1025825-38-0
Molecular Formula	C4H7BF3KO2
Molecular Weight	193.99 g/mol
Synonyms	Potassium (E)-3-Methoxy-1-propenyltrifluoroborate; Potassium (E)-3-Methoxyallyltrifluoroborate; (E)-3-Methoxyprop-1-en-1-yltrifluoroborate Potassium Salt; Potassium Trifluoro((E)-3-methoxyprop-1-en-1-yl)borate; (E)-Potassium 3-Methoxyallyltrifluoroborate; K-3-Methoxyallyltrifluoroborate (E-isomer); Potassium (E)-β-Methoxyvinyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (E)-3-Methoxyprop-1-Enyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0 %
NMR Purity (¹H)	≥ 97%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E:Z)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.