Description

Methyl 5-Methyl-4-Furancarboxylate-2-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functionalized heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing functionalized furan or aryl moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers via cross-coupling methodologies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for introducing the 5-methyl-4-furancarboxylate fragment into complex molecular frameworks.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Process Chemistry & Scale-Up: A reliable intermediate for optimizing and scaling the production of target molecules from milligram to kilogram scale.

Basic Information

Item	Details
Product Name	Methyl 5-Methyl-4-Furancoxylate-2-Boronic Acid Pinacol Ester
CAS No.	1025719-05-4
Molecular Formula	C₁₃H₂₁BO₅
Molecular Weight	268.12 g/mol
Synonyms	5-Methyl-4-(methoxycarbonyl)furan-2-boronic acid pinacol ester; Methyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-furoate; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methyl-4-furancarboxylic acid methyl ester; 4-Methoxycarbonyl-5-methylfuran-2-boronic acid pinacol ester; MFBPE; (5-Methyl-4-(methoxycarbonyl)furan-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our Methyl 5-Methyl-4-Furancarboxylate-2-Boronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, which is critical for reproducible research and process development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates and fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.