Description

3-(Methoxycarbonyl)Pyridine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery, catalyst development, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron reagent for forming carbon-carbon bonds between aromatic and heteroaromatic systems under mild conditions.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	3-(Methoxycarbonyl)Pyridine-5-Boronic Acid, Pinacol Ester
CAS No.	1025718-91-5
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinic acid methyl ester; Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate; 3-Carbomethoxypyridine-5-boronic acid pinacol ester; Methyl 5-(pinacolatoboryl)nicotinate; 5-(Pinacolatoboryl)nicotinic acid methyl ester; Nicotinic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-(Methoxycarbonyl)Pyridine-5-Boronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure it meets the stringent purity and consistency standards required for research and commercial synthesis. Our quality assurance protocols include HPLC, NMR, and mass spectrometry to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.