Description

2-Cyanopyrimidine-5-Boronic Acid Pinacol Ester is a high-purity, multifunctional boronic ester derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel pyrimidine-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Enables the synthesis of organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology: Serves as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Library Synthesis: Facilitates high-throughput parallel synthesis for creating diverse compound libraries in medicinal chemistry.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	2-Cyanopyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	1025708-31-9
Molecular Formula	C11H14BN3O2
Molecular Weight	231.06 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carbonitrile; 2-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Cyanopyrimidin-5-ylboronic Acid Pinacol Ester; 2-CN-Pyrimidine-5-Bpin; (2-Cyanopyrimidin-5-yl)boronic Acid Pinacol Ester; 5-Borono-2-cyanopyrimidine Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Cyanopyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.