Description

Ethyl 2-Bromobenzoate-6-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. This compound is specifically engineered to serve as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging the boronic ester functionality for selective bond formation.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as OLEDs and organic semiconductors, where the bromo and boronate groups allow for controlled polymerization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring functionalized benzoate derivatives with orthogonal reactivity.

Basic Information

Product Name	Ethyl 2-Bromobenzoate-6-Boronic Acid Pinacol Ester
CAS No.	1025708-01-3
Molecular Formula	C15H20BBrO4
Molecular Weight	355.04 g/mol
Synonyms	2-Bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Ethyl Ester; Ethyl 2-Bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 6-Borono-2-bromobenzoic Acid Ethyl Ester Pinacol Ester; 2-Bromo-6-(pinacolatoboryl)benzoic Acid Ethyl Ester; Ethyl 2-Bromo-6-pinacolatoboronobenzoate; (2-Bromo-6-(ethoxycarbonyl)phenyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromobenzoate-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.