Description

3,4-Dihydro-2H-Pyran-6-Boronic Acid Pinacol Ester is a high-purity organoboron building block, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is a critical reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex heterocyclic scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for the formation of biaryl and other C-C bonds under mild conditions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A reliable starting material for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	3,4-Dihydro-2H-Pyran-6-Boronic Acid Pinacol Ester
CAS No.	1025707-93-0
Molecular Formula	C11H19BO3
Molecular Weight	210.08 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyran; 2H-Pyran-6-boronic acid, 3,4-dihydro-, pinacol ester; 3,4-Dihydro-2H-pyran-6-ylboronic acid pinacol ester; 6-(Pinacolatoboryl)-3,4-dihydro-2H-pyran; DHP-BPin; 2,3-Dihydro-4H-pyran-6-boronic acid pinacol ester; 3,4-Dihydro-2H-pyran-6-boronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-Pyran-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.