Description

[4-(1-Azetidinylcarbonyl)Phenyl]-Boronic Acid is a high-purity boronic acid derivative featuring an azetidine carbonyl moiety, making it a valuable building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring biaryl structures.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile organoboron partner for palladium-catalyzed coupling with aryl/vinyl halides or triflates.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the development of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology & Proteomics: Can be utilized in the design of molecular probes and inhibitors for target identification and validation.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	[4-(1-Azetidinylcarbonyl)Phenyl]-Boronic Acid
CAS No.	1025664-36-1
Molecular Formula	C10H12BNO3
Molecular Weight	205.02 g/mol
Synonyms	4-(Azetidine-1-carbonyl)phenylboronic acid; [4-(Azetidin-1-ylcarbonyl)phenyl]boronic acid; (4-(Azetidine-1-carbonyl)phenyl)boronic acid; B-[4-(1-Azetidinylcarbonyl)phenyl]boronic acid; 4-(1-Azetidinecarbonyl)benzeneboronic acid; Azetidine-1-carboxylic acid [4-(dihydroxyboryl)phenyl] ester
EINECS	Contact for details

Quality Control

Our [4-(1-Azetidinylcarbonyl)Phenyl]-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.