Description

B-(3'-Chloro[1,1'-Biphenyl]-4-Yl)Boronic Acid CAS NO 1025496-32-5 is a high-purity, synthetically valuable boronic acid derivative, serving as a critical building block in modern cross-coupling reactions. Its primary value lies in enabling the precise construction of complex biaryl structures, which are central to advanced material and pharmaceutical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chlorinated biaryl motifs.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where the biphenyl unit contributes to desired electronic or structural properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for methodological development in palladium-catalyzed cross-coupling reactions.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Detail
Product Name	B-(3'-Chloro[1,1'-Biphenyl]-4-Yl)Boronic Acid
CAS No.	1025496-32-5
Molecular Formula	C12H10BClO2
Molecular Weight	232.47 g/mol
Synonyms	(3'-Chloro[1,1'-biphenyl]-4-yl)boronic acid; 4-(3-Chlorophenyl)phenylboronic acid; [1,1'-Biphenyl]-4-boronic acid, 3'-chloro-; 3'-Chloro-4-biphenylboronic acid; 3-Chlorobiphenyl-4-boronic acid; (3'-Chlorobiphenyl-4-yl)boronic acid; B-(3'-Chloro-4-biphenylyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of B-(3'-Chloro[1,1'-Biphenyl]-4-Yl)Boronic Acid is manufactured and tested under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.