Description

5-Acetyl-2-Chlorophenylboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, catalyst development, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic motifs.
• Material Science: Employed in the development of organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs) where its boronic acid and acetyl groups facilitate polymerization and functionalization.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for methodology development, catalyst testing, and library synthesis for high-throughput screening.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form new carbon-carbon bonds with various organic halides.

Basic Information

Product Name	5-Acetyl-2-Chlorophenylboronic Acid
CAS No.	1022922-17-3
Molecular Formula	C8H8BClO3
Molecular Weight	198.41 g/mol
Synonyms	(5-Acetyl-2-chlorophenyl)boronic acid; 2-Chloro-5-acetylbenzeneboronic acid; 5-Acetyl-2-chlorobenzeneboronic acid; 2-Chloro-5-acetylphenylboronic acid; Boronic acid, B-(5-acetyl-2-chlorophenyl)-; 1022922-17-3; AKOS006361889
EINECS	Contact for details

Quality Control

Every batch of 5-Acetyl-2-Chlorophenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.