Description

(2-Amino-5-Trifluoromethyl-3H-Imidazol-4-Yl)-Phenyl-Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylated imidazole core structure. This compound is critical for research and development in medicinal chemistry, where its specific functional groups enable the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic effects.
• Fluorinated Compound Synthesis: Serves as a versatile precursor for introducing the trifluoromethyl group into more complex molecular architectures.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, high-performance crop protection agents.
• Material Science Research: Investigated for use in the development of specialty polymers or organic electronic materials due to its conjugated system.

Basic Information

Product Name	(2-Amino-5-Trifluoromethyl-3H-Imidazol-4-Yl)-Phenyl-Methanone
CAS No.	1021875-67-1
Molecular Formula	C11H8F3N3O
Molecular Weight	255.20 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)-1H-imidazole-4-carboxaldehyde; 4-Benzoyl-2-amino-5-(trifluoromethyl)imidazole; (2-Amino-5-trifluoromethyl-1H-imidazol-4-yl)-phenyl-methanone; 2-Amino-α-phenyl-5-(trifluoromethyl)-4-imidazolemethanol (keto form); 4-Benzoyl-2-amino-5-trifluoromethylimidazole; Phenyl(2-amino-5-trifluoromethyl-1H-imidazol-4-yl)methanone
EINECS	Contact for details

Quality Control

Our (2-Amino-5-Trifluoromethyl-3H-Imidazol-4-Yl)-Phenyl-Methanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.