Description

Triclosan-D3 is a stable isotope-labeled analog of the broad-spectrum antimicrobial agent triclosan, specifically deuterated at three positions. This compound is an essential internal standard for the accurate quantification of triclosan in complex matrices using advanced analytical techniques like LC-MS/MS and GC-MS. It is primarily required by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in method development, environmental monitoring, and pharmacokinetic studies to ensure precise and reliable results.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical deuterated internal standard for the precise quantification of triclosan in LC-MS/MS and GC-MS analyses.
• Environmental Analysis: Used in the detection and measurement of triclosan residues in water, soil, and wastewater treatment plant effluents.
• Biomedical and Clinical Research: Enables accurate pharmacokinetic and bio-monitoring studies of triclosan exposure in human tissues, blood, and urine.
• Consumer Product Testing: Facilitates the analysis of triclosan content in personal care products like soaps, toothpaste, and cosmetics for regulatory compliance.
• Food Safety and Toxicology: Applied in research to trace and quantify triclosan migration from packaging materials or its presence in food products.
• Method Development and Validation: Essential for developing, optimizing, and validating robust analytical methods in quality control and research laboratories.

Basic Information

Product Name	Triclosan-D3
CAS No.	1020719-98-5
Molecular Formula	C12H4D3Cl3O2
Molecular Weight	291.56 g/mol (approximate)
Synonyms	5-Chloro-2-(2,4-dichlorophenoxy)phenol-d3; 2,4,4'-Trichloro-2'-hydroxydiphenyl ether-d3; Deuterated Triclosan; Triclosan (phenyl-D3); Irgasan-D3; CH-3565-d3; Lexol 300-d3; Ster-Zac-d3
EINECS	Contact for details

Quality Control

Our Triclosan-D3 is manufactured under strict quality protocols to ensure high chemical purity and isotopic enrichment, which are critical for its performance as an internal standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity, chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for reference materials to ensure reliable and reproducible analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity (by NMR)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.