Description

Sulfamethazine-D4 is a deuterated analog of the sulfonamide antibiotic sulfamethazine, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, veterinary medicine, and food safety sectors who require precise measurement of sulfamethazine residues and metabolites.

Application

• Internal Standard for LC-MS/MS: Primary application for the accurate quantification of sulfamethazine in complex biological and environmental matrices.
• Veterinary Drug Residue Analysis: Used in testing for sulfonamide residues in meat, milk, eggs, and honey to ensure food safety and regulatory compliance.
• Pharmacokinetic and Metabolite Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in research.
• Pharmaceutical Quality Control: Supports assay validation and impurity profiling in the manufacturing of sulfonamide-based pharmaceuticals.
• Environmental Monitoring: Aids in the detection and quantification of antibiotic pollutants in water and soil samples.
• Clinical Research: Facilitates therapeutic drug monitoring and biomedical research involving sulfamethazine.

Basic Information

Product Name	Sulfamethazine-D4
CAS No.	1020719-82-7
Molecular Formula	C12H10D4N4O2S
Molecular Weight	282.35 g/mol
Synonyms	4-Amino-N-(4,6-dimethyl-2-pyrimidinyl-d4)benzenesulfonamide; Sulfadimidine-D4; Deuterated Sulfamethazine; [2H4]-Sulfamethazine; SMZ-D4; Sulfamethazine (phenyl-D4); Sulfadimidine (phenyl-D4); N1-(4,6-Dimethyl-2-pyrimidinyl-d4)sulfanilamide
EINECS	Contact for details

Quality Control

Every batch of Sulfamethazine-D4 is manufactured and analyzed to meet the stringent requirements for isotopic purity and chemical purity demanded by advanced analytical laboratories. Our quality assurance includes comprehensive testing via NMR, HPLC, and MS to confirm isotopic enrichment (>98% D) and chemical identity. Certificates of Analysis (COA) detailing lot-specific results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.