Description

Sulfadimethoxine-D4 is a deuterated internal standard of the sulfonamide antibiotic sulfadimethoxine, specifically labeled with four deuterium atoms. This compound is critically important for ensuring the accuracy and reliability of quantitative mass spectrometry analyses in complex matrices. It is an essential tool for analytical laboratories and research institutions conducting method development and validation for veterinary drug residue testing, food safety monitoring, and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard for the analysis of sulfadimethoxine and related sulfonamides in food, feed, and biological samples.
• Veterinary Drug Residue Testing: Used in method development and routine testing to monitor compliance with maximum residue limits (MRLs) in meat, milk, eggs, and honey.
• Pharmaceutical Research: Supports pharmacokinetic and metabolic studies of sulfadimethoxine in animal models.
• Environmental Analysis: Aids in the detection and quantification of sulfadimethoxine residues in environmental water samples.
• Method Validation & Quality Control: Essential for validating analytical methods according to international guidelines (e.g., EU 2021/808, FDA) and ensuring data integrity in contract research organizations (CROs).
• Reference Material Production: Serves as a key component in the preparation of certified reference materials (CRMs) and quality control samples.

Basic Information

Product Name	Sulfadimethoxine-D4
CAS No.	1020719-80-5
Molecular Formula	C12H10D4N4O4S
Molecular Weight	314.36 g/mol
Synonyms	4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide-2',3',5',6'-d4; Sulfadimethoxine-d4; [2H4]-Sulfadimethoxine; Sulfadimethoxine (phenyl-d4); Deuterated Sulfadimethoxine; SDM-d4; Sulfadimethoxine Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Sulfadimethoxine-D4 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and isotopic enrichment meet the exacting standards required for analytical applications. A detailed Certificate of Analysis (COA) is supplied with each product, reporting results for assay, isotopic purity, and related substances by HPLC and/or LC-MS. Our quality commitment supports compliance with ISO 17025 and GMP principles for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (LC-MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.