Description

2-[3-(Cyclopropanesulfonyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, enabling the introduction of the cyclopropanesulfonylphenyl moiety.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses producing bespoke compounds for client projects.
• Academic & R&D Laboratories: Employed in methodological development and the synthesis of complex natural product analogs or novel chemical entities.

Basic Information

Product Name	2-[3-(Cyclopropanesulfonyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1020206-37-4
Molecular Formula	C15H21BO4S
Molecular Weight	308.20 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonylcyclopropane; [3-(Cyclopropanesulfonyl)phenyl]boronic acid pinacol ester; (3-Cyclopropanesulfonylphenyl)boronic acid pinacol ester; 2-(3-Cyclopropanesulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Cyclopropanesulfonyl)phenylboronic acid pinacol ester; Cyclopropanesulfonylphenylboronic acid pinacol ester; CAS 1020206-37-4
EINECS	Contact for details

Quality Control

Every batch of 2-[3-(Cyclopropanesulfonyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems to ensure consistency and reliability for critical R&D and production applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and GC-MS. Our quality commitment aligns with the standards required for pharmaceutical and advanced material development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.