Description

1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, synthetically versatile organoboron building block. This compound is critical for modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry, agrochemical development, and advanced materials science.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in pharmaceutical intermediates.
• Medicinal Chemistry & Drug Discovery: Used as a versatile building block for creating novel heterocyclic compounds and potential active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides due to the pyrazole core's bioactivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and functional polymers.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and tags for studying biological systems.
• Scale-up Process Development: Supplied for pilot plant and commercial-scale manufacturing of fine chemicals and specialty materials.

Basic Information

Product Name	1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1020174-04-2
Molecular Formula	C10H17BN2O2
Molecular Weight	208.07 g/mol
Synonyms	1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Methyl-1H-pyrazole-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrazole; 1-Methyl-3-(pinacolboryl)-1H-pyrazole; 1-Methylpyrazole-3-boronic acid pinacol ester; Pyrazole-3-boronic acid pinacol ester, 1-methyl-; 1-Methyl-1H-pyrazole-3-boronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity during use. Recommended storage temperature: 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.