Description

1-Nitro-4-[4-(Trifluoromethoxy)Phenyl]Benzene is a high-purity, specialized aromatic compound featuring both nitro and trifluoromethoxy functional groups, making it a valuable intermediate for advanced synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific electronic and steric properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for creating advanced organic electronic materials, where its rigid, substituted biphenyl core is integral to molecular design.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and high-performance resins, contributing unique thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nitro-group transformations in academic and industrial R&D settings.

Basic Information

Product Name	1-Nitro-4-[4-(Trifluoromethoxy)Phenyl]Benzene
CAS No.	1019996-86-1
Molecular Formula	C13H8F3NO3
Molecular Weight	283.21 g/mol
Synonyms	4'-(Trifluoromethoxy)-4-nitro-1,1'-biphenyl; 4-Nitro-4'-(trifluoromethoxy)biphenyl; [1,1'-Biphenyl]-4-nitro-4'-(trifluoromethoxy)-; 4-(4-Nitrophenyl)(trifluoromethoxy)benzene; 4-Nitro-4'-trifluoromethoxybiphenyl; p-Nitro-p'-(trifluoromethoxy)biphenyl
EINECS	Contact for details

Quality Control

Our 1-Nitro-4-[4-(Trifluoromethoxy)Phenyl]Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.