Description

2-Chloro-n-Cyclopropyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-value, multi-functional chemical intermediate featuring a boronic ester pinacol group. This compound matters for its critical role as a key building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients and functional molecules through efficient cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionality.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and bioconjugation reagents.
• Academic & Industrial R&D: Essential for method development and library synthesis in medicinal chemistry and drug discovery programs.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Item	Details
Product Name	2-Chloro-n-Cyclopropyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1019918-90-1
Molecular Formula	C18H25BClNO3
Molecular Weight	349.66 g/mol
Synonyms	2-Chloro-N-cyclopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 5-Boronic acid pinacol ester, 2-chloro-N-cyclopropyl-4-methylbenzamide; Benzamide, 2-chloro-N-cyclopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (5-(2-Chloro-N-cyclopropyl-4-methylbenzamido)-2-methylphenyl)boronic acid pinacol ester; CAS 1019918-90-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Cyclopropyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.