Description

N,4-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern synthetic organic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in pharmaceuticals and organic materials.
• Pharmaceutical Intermediate: Serves as a versatile building block in the research and production of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific aryl-aryl linkages are required.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology & Proteomics: Can be utilized as a handle for bioconjugation or in the synthesis of molecular probes and inhibitors.
• Custom Synthesis & Process Development: A valuable starting material for contract research organizations (CROs) and CDMOs scaling up synthetic routes.

Basic Information

Product Name	N,4-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1019918-76-3
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	3-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl))-N,4-dimethylbenzamide; N,4-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,4-dimethylbenzamide; 1019918-76-3; Benzamide, N,4-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol N,4-Dimethyl-3-boronobenzamide
EINECS	Contact for details

Quality Control

Every batch of N,4-Dimethyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.