Description

5'-Fluoro-2'-(1-Piperidyl)Acetophenone is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is critical for the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially those targeting neurological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a precursor for creating more complex piperidine- and acetophenone-containing compounds.
• API Development: Integral in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and synthetic organic chemistry research.

Basic Information

Product Name	5'-Fluoro-2'-(1-Piperidyl)Acetophenone
CAS No.	1019622-03-7
Molecular Formula	C13H16FNO
Molecular Weight	221.27 g/mol
Synonyms	1-[2-Fluoro-5-(1-piperidinyl)phenyl]ethanone; 1-(5-Fluoro-2-piperidin-1-ylphenyl)ethan-1-one; 2'-Fluoro-5'-(1-piperidyl)acetophenone; 5-Fluoro-2-piperidin-1-ylacetophenone; 1019622-03-7; Ethanone, 1-[2-fluoro-5-(1-piperidinyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-(1-Piperidyl)Acetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.