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2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine CAS NO 1018953-88-2


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CAS No.:1018953-88-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine is a high-value organoboron building block, specifically a pinacol boronate ester derivative of a thienopyridine heterocycle. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily needed by pharmaceutical R&D and agrochemical research teams for constructing complex molecular architectures in drug discovery and advanced material science.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the thienopyridine pharmacophore.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
  • Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
  • Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
  • Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences industry.

Basic Information

Item Details
Product Name 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine
CAS No. 1018953-88-2
Molecular Formula C15H18BNO2S
Molecular Weight 287.19 g/mol
Synonyms Thieno[3,2-c]pyridine-2-boronic acid pinacol ester; 2-(Thieno[3,2-c]pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thieno[3,2-c]pyridine; Pinacol Thieno[3,2-c]pyridine-2-boronate; 1018953-88-2; Thieno[3,2-c]pyridine-2-boronic acid, pinacol ester
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Quality Control

Our production of 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine adheres to stringent internal quality standards designed for research and process chemistry. Every batch is characterized by NMR (¹H, ¹³C, ¹¹B) and HPLC to ensure structural identity and high purity. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and potential decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥95% (Area %)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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