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2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine CAS NO 1018953-88-2
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CAS No.:1018953-88-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine is a high-value organoboron building block, specifically a pinacol boronate ester derivative of a thienopyridine heterocycle. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily needed by pharmaceutical R&D and agrochemical research teams for constructing complex molecular architectures in drug discovery and advanced material science.
Application
- Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the thienopyridine pharmacophore.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
- Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
- Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
- Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
- Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences industry.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine |
| CAS No. | 1018953-88-2 |
| Molecular Formula | C15H18BNO2S |
| Molecular Weight | 287.19 g/mol |
| Synonyms | Thieno[3,2-c]pyridine-2-boronic acid pinacol ester; 2-(Thieno[3,2-c]pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thieno[3,2-c]pyridine; Pinacol Thieno[3,2-c]pyridine-2-boronate; 1018953-88-2; Thieno[3,2-c]pyridine-2-boronic acid, pinacol ester |
| EINECS | Contact for details |
Quality Control
Our production of 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[3,2-C]Pyridine adheres to stringent internal quality standards designed for research and process chemistry. Every batch is characterized by NMR (¹H, ¹³C, ¹¹B) and HPLC to ensure structural identity and high purity. Certificates of Analysis (COA) with full analytical data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and potential decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥95% (Area %) |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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